Ogólnoustrojowe dostarczanie ukierunkowane nanoterapii odwraca tętniaki

Ogólnoustrojowe dostarczanie ukierunkowane nanoterapii odwraca tętniaki aorty brzusznej wywołane przez angiotensynę II u myszy

Choroba tętniaka aorty brzusznej (AAA) powoduje rozszerzenie aorty, co prowadzi do pęknięcia aorty i śmierci, jeśli nie jest wcześnie leczona. Jest to 14. najczęstsza przyczyna zgonów w Stanach Zjednoczonych i 10. najczęstsza przyczyna zgonów mężczyzn w wieku powyżej 55 lat, dotykająca tysiące pacjentów.

Pomimo rozpowszechnienia AAA, nie ma bezpiecznych i skutecznych farmakoterapii dla pacjentów. Uszkodzenie elastycznej blaszki ściany tętniaka jest stałą cechą AAA, co czyni go idealnym celem do dostarczania leków do miejsca tętniaka. W tym badaniu  połączyliśmy  nanocząstki z przeciwciałem elastyny,   które celuje tylko w zdegradowaną elastynę, oszczędzając jednocześnie zdrową elastynę.

Po wywołaniu tętniaka przez 4-tygodniową infuzję angiotensyny II (Ang II), dwa dwutygodniowe dożylne wstrzyknięcia nanocząsteczek obłożonych pentagalloiloglukozą (PGG)  sprzężonych  z przeciwciałem elastyny   dostarczyły lek do miejsca tętniaka. Pokazujemy, że ukierunkowane dostarczenie PGG może odwrócić rozszerzenie aorty, złagodzić stan zapalny, przywrócić elastyczną blaszkę i poprawić właściwości mechaniczne aorty w miejscu AAA. Dlatego prosta terapia dożylna nanocząsteczek obciążonych PGG może być skuteczną opcją leczenia tętniaków we wczesnym i średnim stadium w celu odwrócenia progresji choroby i przywrócenia aorty do normalnej homeostazy.

Błąd połączenia.

Glikoinżynieria przeciwciało i przygotowanie koniugatu homogenicznego przeciwciało-lek

 

Koniugaty przeciwciało- lek (ADC) to klasa biofarmaceutyków, w których środki cytotoksyczne są  sprzężone  z przeciwciałami  monoklonalnymi  (mAb), umożliwiając ukierunkowane dostarczanie leków. Obecne ADC heterogeniczne ( sprzężone  w losowych pozycjach zmiennych), cierpiała od kwestii stabilności, powtarzalności, skuteczność, itp Ostatnie postępy doprowadziły do opracowania preparatów jednorodnych ADC przez miejscowo specyficzną koniugacji, co pozwala na sterowanie lek To- przeciwciała  stosunek . Podejścia te zwiększyły okno terapeutyczne, skuteczność i powtarzalność serii preparatów ADC. Przeciwciała  niosą parę heterogennych N-glikanów w regionach Fc, które są krytyczne dla  przeciwciała funkcjonować.

Koniugację leków za pomocą glikoinżynierii osiągnięto różnymi podejściami, w tym z użyciem endo-β-N-acetyloglukozaminidazy (ENGazy) i mutantów transferazy monosacharylowej. W tym artykule podsumowujemy różne podejścia  inżynierii glikemicznej do koniugacji przeciwciało -lek i omawiamy ich zalety w opracowywaniu homogenicznych ADC nowej generacji.

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Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled

AP-301-F 1 mg Ask for price

Alexa Fluor® 488 anti-rat CD103 (αE Integrin)

E16FRG103-100U 100 μg
EUR 801.67
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-rat CD103 (αE Integrin)

E16FRK103-100U 100 μg
EUR 801.67
Description: Available in various conjugation types.

Alexa Fluor® 488 anti-human CD103 (Integrin αE)

E16FHG103-100 100 tests
EUR 1235
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD103 (Integrin αE)

E16FHK103-025 25 tests
EUR 628.33
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD103 (Integrin αE)

E16FHK103-100 100 tests
EUR 1235
Description: Available in various conjugation types.

MOUSE ANTI HUMAN INTEGRIN ALPHA V BETA 5

MBS211733-01mg 0.1mg
EUR 1240

MOUSE ANTI HUMAN INTEGRIN ALPHA V BETA 5

MBS211733-5x01mg 5x0.1mg
EUR 5410

Integrin Antibody (alpha V beta 5)

GWB-262158 0.1 mg Ask for price

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-01mg 0.1 mg
EUR 1095.6

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-100tests 100 tests Ask for price

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-25tests 25 tests
EUR 912.5

Integrin Alpha V + Beta 5 Antibody Cy3 Conjugated

MBS9460624-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody Cy3 Conjugated

MBS9460624-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 5 Antibody Cy5 Conjugated

MBS9460625-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody Cy5 Conjugated

MBS9460625-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 5 Antibody FITC Conjugated

MBS9460623-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody FITC Conjugated

MBS9460623-5x01mL 5x0.1mL
EUR 2525

Mouse Anti Human Integrin Alpha V Beta 5 Monoclonal Antibody

CABT-49626MH 0.1 mg
EUR 1650

Integrin alpha V beta 6 antibody

10R-11286 100 ug
EUR 838
Description: Mouse Monoclonal Integrin alpha V beta 6 antibody

Integrin alpha V + beta 6 Antibody

V8494-100UG 100 ug
EUR 424.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V + beta 6 Antibody

V8494-20UG 20 ug
EUR 186.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V + beta 6 Antibody

V8494SAF-100UG 100 ug
EUR 424.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V beta 6 antibody

MBS838523-01mg 0.1mg
EUR 1425

Integrin alpha V beta 6 antibody

MBS838523-5x01mg 5x0.1mg
EUR 6265

alpha (v) beta (3) INTEGRIN, Antibody

GWB-CB9AC3 0.1 mg Ask for price

Integrin alpha-V / Integrin Beta-3 (ITGAV / ITGB3) Antibody

abx140635-100g 100 µg
EUR 287.5

Streptavidin-Alexa594 (Alexas fluor 594) conjugate

SV-A594-100 100 tests
EUR 270

Integrin alpha-V/Integrin beta-3 (ITGAV/ITGB3) Antibody (PE)

abx347194-100l 100 µl Ask for price

Integrin alpha-V/Integrin beta-3 (ITGAV/ITGB3) Antibody (PE)

abx347194-50l 50 µl
EUR 400

Integrin Alpha V + Beta 3 (CD51+CD61)

E8ER1911-52 100ul
EUR 275
Description: Available in various conjugation types.

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mL 0.1mL
EUR 345

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF405L 0.1mL(AF405L)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF405S 0.1mL(AF405S)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF610 0.1mL(AF610)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF635 0.1mL(AF635)
EUR 565

Integrin Alpha V + Beta 3 Antibody HRP Conjugated

MBS9460564-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody HRP Conjugated

MBS9460564-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 3 Antibody Cy3 Conjugated

MBS9460566-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody Cy3 Conjugated

MBS9460566-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 3 Antibody Cy5 Conjugated

MBS9460567-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody Cy5 Conjugated

MBS9460567-5x01mL 5x0.1mL
EUR 2525

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)

50336 0.5 ml
EUR 270

Integrin Alpha V + Beta 3 Antibody FITC Conjugated

MBS9460565-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody FITC Conjugated

MBS9460565-5x01mL 5x0.1mL
EUR 2525

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

MBS696539-005mg 0.05mg
EUR 215

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

MBS696539-5x005mg 5x0.05mg
EUR 925

Alexa Fluor® 594 anti-mouse CD3

E16FMJ003-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD4

E16FMJ004-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD3

E16FHJ003-100U 100ug
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD4

E16FHJ004-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD8a

E16FMJ008a-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD18

E16FMJ018-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD19

E16FMJ019-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD31

E16FMJ031-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD45

E16FMJ045-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD68

E16FMJ068-100U 100 μg
EUR 1365
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD8a

E16FHJ008a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD14

E16FHJ0142-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD19

E16FHJ019-100U 100 μg
EUR 1083.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD11c

E16FMJ011c-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD106

E16FMJ106-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11a

E16FHJ011a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11b

E16FHJ011b-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Mouse Anti-Human IgA - Alexa Fluor 594

DL87387A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

DL87387A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

DL87390A-100ul 100 ul
EUR 155
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

DL87390A-500ul 500 ul
EUR 350
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

E38A3634 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 594

E38A3638 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-1ml 1 ml
EUR 480
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-500ul 500 ul
EUR 290
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Danio rerio integrin, beta 1b (ITGB1B) IgG (aff pure)

AB-23236-A 100ug
EUR 578.4

Rabbit Anti-Human IgM - Alexa Fluor 594

DL87379A-100ul 100 ul
EUR 190
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

DL87379A-500ul 500 ul
EUR 280
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

E38A3625 100μL
EUR 125

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-1ml 1 ml
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-500ul 500 ul
EUR 210
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415500-02mg 0.2 mg
EUR 678

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415501-01mg 0.1 mg
EUR 526.8

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415500-200l 200 µl
EUR 462.5

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415501-200l 200 µl
EUR 337.5

Integrin Alpha V/Beta 1 Polyclonal Antibody PE Conjugated

MBS9463175-01mL 0.1mL
EUR 595

Integrin Alpha V/Beta 1 Polyclonal Antibody PE Conjugated

MBS9463175-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V/Beta 1 Polyclonal Antibody Bio Conjugated

MBS9463174-01mL 0.1mL
EUR 595

Integrin Alpha V/Beta 1 Polyclonal Antibody Bio Conjugated

MBS9463174-5x01mL 5x0.1mL
EUR 2525

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-48StripWells 48-Strip-Wells
EUR 550

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-96StripWells 96-Strip-Wells
EUR 765

Cat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349958-INQUIRE INQUIRE Ask for price

Duck Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9364315-INQUIRE INQUIRE Ask for price

Goat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9358501-INQUIRE INQUIRE Ask for price

Cavy Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9366808-INQUIRE INQUIRE Ask for price

Fish Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9346553-INQUIRE INQUIRE Ask for price

Anti-Alpha v Beta Integrin antibody

STJ16100153 1 mL
EUR 864

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-10x96StripWells 10x96-Strip-Wells
EUR 3290

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-48StripWells 48-Strip-Wells
EUR 295

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-5x96StripWells 5x96-Strip-Wells
EUR 1800

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-96StripWells 96-Strip-Wells
EUR 450

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-01mg 0.1mg
EUR 660

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-05mg 0.5mg
EUR 1695

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-1mg 1mg
EUR 2370

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-5mg 5mg
EUR 7845

Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant

P1121-10 each Ask for price

Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant

P1121-50 each Ask for price

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-48StripWells 48-Strip-Wells
EUR 550

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-96StripWells 96-Strip-Wells
EUR 765

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-48StripWells 48-Strip-Wells
EUR 550

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-96StripWells 96-Strip-Wells
EUR 765

Plant Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9370277-INQUIRE INQUIRE Ask for price

Goose Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349080-INQUIRE INQUIRE Ask for price

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-48StripWells 48-Strip-Wells
EUR 550

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-96StripWells 96-Strip-Wells
EUR 765

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-48StripWells 48-Strip-Wells
EUR 550

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-96StripWells 96-Strip-Wells
EUR 765

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-10x96StripWells 10x96-Strip-Wells
EUR 3545

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-48StripWells 48-Strip-Wells
EUR 310

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-5x96StripWells 5x96-Strip-Wells
EUR 1940

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-96StripWells 96-Strip-Wells
EUR 475

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-48StripWells 48-Strip-Wells
EUR 285

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-96StripWells 96-Strip-Wells
EUR 405

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-10x96StripWells 10x96-Strip-Wells
EUR 3290

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-48StripWells 48-Strip-Wells
EUR 295

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-5x96StripWells 5x96-Strip-Wells
EUR 1800

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-96StripWells 96-Strip-Wells
EUR 450

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS212234-02mg 0.2mg
EUR 500

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS212234-5x02mg 5x0.2mg
EUR 2070

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS215105-0025mg 0.025mg
EUR 210

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS215105-5x0025mg 5x0.025mg
EUR 765

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS213386-01mg 0.1mg
EUR 920

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS213386-5x01mg 5x0.1mg
EUR 3965

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-48StripWells 48-Strip-Wells
EUR 550

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-96StripWells 96-Strip-Wells
EUR 765

Donkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9343685-INQUIRE INQUIRE Ask for price

Pigeon Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349426-INQUIRE INQUIRE Ask for price

Rabbit Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349793-INQUIRE INQUIRE Ask for price

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-48StripWells 48-Strip-Wells
EUR 550

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-96StripWells 96-Strip-Wells
EUR 765

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-48StripWells 48-Strip-Wells
EUR 550

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-96StripWells 96-Strip-Wells
EUR 765

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-10x96StripWells 10x96-Strip-Wells
EUR 3545

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-48StripWells 48-Strip-Wells
EUR 310

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-5x96StripWells 5x96-Strip-Wells
EUR 1940

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-96StripWells 96-Strip-Wells
EUR 475

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-10x96StripWells 10x96-Strip-Wells
EUR 3955

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-48StripWells 48-Strip-Wells
EUR 305

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-5x96StripWells 5x96-Strip-Wells
EUR 2005

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-96StripWells 96-Strip-Wells
EUR 475

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-48StripWells 48-Strip-Wells
EUR 550

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-96StripWells 96-Strip-Wells
EUR 765

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-48StripWells 48-Strip-Wells
EUR 550

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-96StripWells 96-Strip-Wells
EUR 765

Chicken Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353364-INQUIRE INQUIRE Ask for price

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-10x96StripWells 10x96-Strip-Wells
EUR 3545

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-48StripWells 48-Strip-Wells
EUR 310

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-5x96StripWells 5x96-Strip-Wells
EUR 1940

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-96StripWells 96-Strip-Wells
EUR 475

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-10x96StripWells 10x96-Strip-Wells
EUR 3545

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-48StripWells 48-Strip-Wells
EUR 310

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-5x96StripWells 5x96-Strip-Wells
EUR 1940

Azotogenaza w Frankia z guzków korzeni Alnus incana (L.) Moench: immunolokalizacja białek Fe i MoFe podczas różnicowania pęcherzyków

 

Lokalizację azotazy badano w guzkach korzeni Alnus incana (L.) Moench w symbiozie z lokalnym źródłem Frankia. Guzki utrwalono w glutaraldehydzie i zatopiono w Epon lub LR White. Ultracienkie skrawki badano za pomocą TEM po inkubacji z surowicami odpornościowymi przeciwko azotazie i przeciwciałom  wtórnym  sprzężonym ze złotem . Zastosowano surowice odpornościowe przeciwko reduktazie dinitrogenazy (białko Fe) z Rhodospirillum rubrum i dinitrogenazę (białko MoFe) z Azotobacter vinelandii. Gęstość znacznika Immunogold w strzępkach i zarodnikach Frankii była niska i podobna do gęstości tkanki roślinnej.

Bardzo młode pęcherzyki bez przegród wykazywały gęstość znacznika białka Fe podobną do gęstości strzępek, podczas gdy młode pęcherzyki z kilkoma, zwykle nieprzekształcającymi się przegrodami, miały znaczną, ale wciąż niską gęstość znacznika. Dojrzałe pęcherzyki, silnie kompartmentalizowane z powodu przegród poprzecznych , zawierały statystycznie istotnie więcej znacznika białka Fe niż wszystkie inne typy komórek. Stare, degenerujące się pęcherzyki zawsze zawierały azotazę, około połowę mniej niż pęcherzyki dojrzałe, ale często więcej niż pęcherzyki młode. Podobnie, znacznik MoFe nie został wykryty w strzępkach, pojawił się u młodych, ale był największy w dojrzałych pęcherzykach. Widać, że różnicowanie pęcherzyków osiąga pewien etap rozwoju przed rozpoczęciem syntezy azotazy.

 

Optyczna spektroskopia emisyjna w plazmie sprzężonej indukcyjnie jako narzędzie oceny testów bocznego

 

Testy przepływu bocznego (LFA) to immunochromatograficzne urządzenia w miejscu opieki, które mają duży wpływ na diagnostykę choroby dzięki szybkiemu, niedrogiem i łatwemu w użyciu współczynnikowi kształtu. Chociaż LFA odniosły sukces jako narzędzia do rozmieszczania w terenie, mają stosunkowo niski restrict wykrywalności w porównaniu z bardziej złożonymi metodami. Co więcej, większość optymalizacji projektowania i produkcji jest osiągana poprzez czasochłonną i zasobochłonną optymalizację siłową. Pomimo zwiększonego zainteresowania produkcją LFA, potrzebne są bardziej ilościowe narzędzia do badania obecnych protokołów produkcyjnych, a tym samym do dalszej optymalizacji i usprawnienia rozwoju tych urządzeń.

W tej pracy skupiamy się na krytycznym składniku LFA, złocie koloidalnym  sprzężonym  z przeciwciałem detekcyjnym  , jednym z najczęściej stosowanych elementów reporterowych. W badaniu tym wykorzystano optyczną spektroskopię emisyjną ze sprzężeniem indukcyjnym (ICP-OES) w połączeniu z czytnikiem przepływu bocznego do ilościowej analizy dystrybucji złota koloidalnego na liniach testu odczytu i kontrolnych, a także resztkowego złota na wkładce koniugatu i innych przepływach przez regiony. Naszym celem jest bardziej rygorystyczne zrozumienie obecnych projektów LFA, a także ilościowe zrozumienie niedociągnięć charakterystyk operacyjnych w celu przyszłej poprawy. Według naszej wiedzy jest to pierwszy przypadek, kiedy ICP-OES został użyty do badania początkowej dystrybucji złota koloidalnego naniewykorzystany LFA i jego redystrybucja po wykonaniu testu. Używając trzech różnych marek dostępnych na rynku LFA przeciw malarii, zmierzono zawartość złota w każdej sekcji LFA przy różnych testowych stężeniach pasożyta.

Zgodnie z oczekiwaniami całkowita masa złota pozostała niezmieniona po zastosowaniu LFA; jednakże całkowita masa początkowego złota i jego redystrybucja różniły się między producentami. Co ważne, te komercyjne projekty LFA mają również pewne nieodłączne nieefektywności ; na przykład tylko 30% całkowitego złota zdeponowanego na LFA marki A wiąże się z liniami testowymi i kontrolnymi, czyli częściami testu zawierającymi sygnał, który można zinterpretować. Korzystając z informacji zebranych za pomocą tej metody, przyszłe urządzenia mogą być bardziej celowo projektowane, aby skupić się na poprawie wydajności wiązania, co skutkuje obniżeniem kosztów, poprawą granic wykrywalności oraz mniejszą zmiennością między testami i producentami.

Wpływ surowicy na elektrochemiczną detekcję testów biologicznych posiadających etykiety nanocząstek Ag

 

Zbadano wpływ surowicy na elektrochemiczną detekcję testów biologicznych posiadających znaczniki detekcji nanocząstek srebra (AgNP). Zbadano zarówno take a look at modelowy , jak i take a look at biologiczny kanapkowy specyficzny dla antygenu dla markera niewydolności serca NT-proBNP. W obu przypadkach znaczniki AgNP były  sprzężone  z przeciwciałem do wykrywania  . Detekcję elektrochemiczną przeprowadzono metodą wymiany galwanicznej / anodowej woltamperometrii strippingowej, w której Au 3+  wymienia się ze znacznikami AgNP . Testy przeprowadzono przy użyciu papierowej platformy elektrodowej.

Testy biologiczne wystawiano na działanie różnych warunków surowicy przed i podczas wykrywania. W tym artykule opisano trzy ważne wyniki. Po pierwsze, testy specyficzne dla modelu i antygenu można było utworzyć w nierozcieńczonej surowicy bez wykrywalnych zakłóceń ze strony składników surowicy. Po drugie, aby osiągnąć maksymalny możliwy sygnał elektrochemiczny, najwyższy procent surowicy, który może pozostać w buforze testowym podczas wykrywania elektrochemicznego, wynosi 0,25%, gdy nie przeprowadza się płukania. Wyniki testu stają się niedokładne, gdy obecne jest 0,50% lub więcej surowicy . Po trzecie, czynniki hamujące wymianę galwaniczną w surowicy prawdopodobnie dotyczą powierzchniowej adsorpcji biomolekuł na znacznikach AgNP, chelatacji Au 3+ według składników surowicy lub obu. Przedstawione tutaj wyniki dostarczają ogólnych wskazówek dotyczących stosowania metalowych znaczników NP w testach elektrochemicznych w płynach biologicznych.

Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled

AP-301-F 1 mg Ask for price

Alexa Fluor® 488 anti-rat CD103 (αE Integrin)

E16FRG103-100U 100 μg
EUR 801.67
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-rat CD103 (αE Integrin)

E16FRK103-100U 100 μg
EUR 801.67
Description: Available in various conjugation types.

Alexa Fluor® 488 anti-human CD103 (Integrin αE)

E16FHG103-100 100 tests
EUR 1235
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD103 (Integrin αE)

E16FHK103-025 25 tests
EUR 628.33
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD103 (Integrin αE)

E16FHK103-100 100 tests
EUR 1235
Description: Available in various conjugation types.

MOUSE ANTI HUMAN INTEGRIN ALPHA V BETA 5

MBS211733-01mg 0.1mg
EUR 1240

MOUSE ANTI HUMAN INTEGRIN ALPHA V BETA 5

MBS211733-5x01mg 5x0.1mg
EUR 5410

Integrin Antibody (alpha V beta 5)

GWB-262158 0.1 mg Ask for price

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-01mg 0.1 mg
EUR 1095.6

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-100tests 100 tests Ask for price

Integrin Alpha V Beta 5 (ITGAV/ITGB5) Antibody

abx411439-25tests 25 tests
EUR 912.5

Integrin Alpha V + Beta 5 Antibody Cy3 Conjugated

MBS9460624-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody Cy3 Conjugated

MBS9460624-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 5 Antibody Cy5 Conjugated

MBS9460625-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody Cy5 Conjugated

MBS9460625-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 5 Antibody FITC Conjugated

MBS9460623-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 5 Antibody FITC Conjugated

MBS9460623-5x01mL 5x0.1mL
EUR 2525

Mouse Anti Human Integrin Alpha V Beta 5 Monoclonal Antibody

CABT-49626MH 0.1 mg
EUR 1650

Integrin alpha V beta 6 antibody

10R-11286 100 ug
EUR 838
Description: Mouse Monoclonal Integrin alpha V beta 6 antibody

Integrin alpha V + beta 6 Antibody

V8494-100UG 100 ug
EUR 424.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V + beta 6 Antibody

V8494-20UG 20 ug
EUR 186.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V + beta 6 Antibody

V8494SAF-100UG 100 ug
EUR 424.15
Description: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Integrin alpha V beta 6 antibody

MBS838523-01mg 0.1mg
EUR 1425

Integrin alpha V beta 6 antibody

MBS838523-5x01mg 5x0.1mg
EUR 6265

alpha (v) beta (3) INTEGRIN, Antibody

GWB-CB9AC3 0.1 mg Ask for price

Integrin alpha-V / Integrin Beta-3 (ITGAV / ITGB3) Antibody

abx140635-100g 100 µg
EUR 287.5

Streptavidin-Alexa594 (Alexas fluor 594) conjugate

SV-A594-100 100 tests
EUR 270

Integrin alpha-V/Integrin beta-3 (ITGAV/ITGB3) Antibody (PE)

abx347194-100l 100 µl Ask for price

Integrin alpha-V/Integrin beta-3 (ITGAV/ITGB3) Antibody (PE)

abx347194-50l 50 µl
EUR 400

Integrin Alpha V + Beta 3 (CD51+CD61)

E8ER1911-52 100ul
EUR 275
Description: Available in various conjugation types.

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mL 0.1mL
EUR 345

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF405L 0.1mL(AF405L)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF405S 0.1mL(AF405S)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF610 0.1mL(AF610)
EUR 565

Integrin Alpha V + Beta 3 (CD51+CD61)

MBS8577841-01mLAF635 0.1mL(AF635)
EUR 565

Integrin Alpha V + Beta 3 Antibody HRP Conjugated

MBS9460564-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody HRP Conjugated

MBS9460564-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 3 Antibody Cy3 Conjugated

MBS9460566-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody Cy3 Conjugated

MBS9460566-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V + Beta 3 Antibody Cy5 Conjugated

MBS9460567-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody Cy5 Conjugated

MBS9460567-5x01mL 5x0.1mL
EUR 2525

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)

50336 0.5 ml
EUR 270

Integrin Alpha V + Beta 3 Antibody FITC Conjugated

MBS9460565-01mL 0.1mL
EUR 595

Integrin Alpha V + Beta 3 Antibody FITC Conjugated

MBS9460565-5x01mL 5x0.1mL
EUR 2525

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

MBS696539-005mg 0.05mg
EUR 215

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

MBS696539-5x005mg 5x0.05mg
EUR 925

Alexa Fluor® 594 anti-mouse CD3

E16FMJ003-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD4

E16FMJ004-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD3

E16FHJ003-100U 100ug
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD4

E16FHJ004-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD8a

E16FMJ008a-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD18

E16FMJ018-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD19

E16FMJ019-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD31

E16FMJ031-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD45

E16FMJ045-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD68

E16FMJ068-100U 100 μg
EUR 1365
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD8a

E16FHJ008a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD14

E16FHJ0142-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD19

E16FHJ019-100U 100 μg
EUR 1083.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD11c

E16FMJ011c-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD106

E16FMJ106-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11a

E16FHJ011a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11b

E16FHJ011b-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Mouse Anti-Human IgA - Alexa Fluor 594

DL87387A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

DL87387A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

DL87390A-100ul 100 ul
EUR 155
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

DL87390A-500ul 500 ul
EUR 350
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

E38A3634 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 594

E38A3638 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-1ml 1 ml
EUR 480
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 594

YLF0361-500ul 500 ul
EUR 290
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 594

YLF0564-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Danio rerio integrin, beta 1b (ITGB1B) IgG (aff pure)

AB-23236-A 100ug
EUR 578.4

Rabbit Anti-Human IgM - Alexa Fluor 594

DL87379A-100ul 100 ul
EUR 190
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

DL87379A-500ul 500 ul
EUR 280
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

E38A3625 100μL
EUR 125

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-1ml 1 ml
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 594

YLF0561-500ul 500 ul
EUR 210
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415500-02mg 0.2 mg
EUR 678

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415501-01mg 0.1 mg
EUR 526.8

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415500-200l 200 µl
EUR 462.5

Integrin Beta 3/Alpha V (ITGB3/ITGAV) Antibody

abx415501-200l 200 µl
EUR 337.5

Integrin Alpha V/Beta 1 Polyclonal Antibody PE Conjugated

MBS9463175-01mL 0.1mL
EUR 595

Integrin Alpha V/Beta 1 Polyclonal Antibody PE Conjugated

MBS9463175-5x01mL 5x0.1mL
EUR 2525

Integrin Alpha V/Beta 1 Polyclonal Antibody Bio Conjugated

MBS9463174-01mL 0.1mL
EUR 595

Integrin Alpha V/Beta 1 Polyclonal Antibody Bio Conjugated

MBS9463174-5x01mL 5x0.1mL
EUR 2525

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-48StripWells 48-Strip-Wells
EUR 550

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363759-96StripWells 96-Strip-Wells
EUR 765

Cat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349958-INQUIRE INQUIRE Ask for price

Duck Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9364315-INQUIRE INQUIRE Ask for price

Goat Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9358501-INQUIRE INQUIRE Ask for price

Cavy Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9366808-INQUIRE INQUIRE Ask for price

Fish Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9346553-INQUIRE INQUIRE Ask for price

Anti-Alpha v Beta Integrin antibody

STJ16100153 1 mL
EUR 864

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-10x96StripWells 10x96-Strip-Wells
EUR 3290

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-48StripWells 48-Strip-Wells
EUR 295

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-5x96StripWells 5x96-Strip-Wells
EUR 1800

Rat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269796-96StripWells 96-Strip-Wells
EUR 450

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-01mg 0.1mg
EUR 660

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-05mg 0.5mg
EUR 1695

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-1mg 1mg
EUR 2370

alpha-V/beta-3 Integrin, Human, mAb BV3

MBS584338-5mg 5mg
EUR 7845

Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant

P1121-10 each Ask for price

Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant

P1121-50 each Ask for price

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-48StripWells 48-Strip-Wells
EUR 550

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362139-96StripWells 96-Strip-Wells
EUR 765

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-48StripWells 48-Strip-Wells
EUR 550

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9359092-96StripWells 96-Strip-Wells
EUR 765

Plant Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9370277-INQUIRE INQUIRE Ask for price

Goose Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349080-INQUIRE INQUIRE Ask for price

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-48StripWells 48-Strip-Wells
EUR 550

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9348117-96StripWells 96-Strip-Wells
EUR 765

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-48StripWells 48-Strip-Wells
EUR 550

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353139-96StripWells 96-Strip-Wells
EUR 765

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-10x96StripWells 10x96-Strip-Wells
EUR 3545

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-48StripWells 48-Strip-Wells
EUR 310

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-5x96StripWells 5x96-Strip-Wells
EUR 1940

Goat Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266932-96StripWells 96-Strip-Wells
EUR 475

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-48StripWells 48-Strip-Wells
EUR 285

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS263599-96StripWells 96-Strip-Wells
EUR 405

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-10x96StripWells 10x96-Strip-Wells
EUR 3290

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-48StripWells 48-Strip-Wells
EUR 295

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-5x96StripWells 5x96-Strip-Wells
EUR 1800

Mouse Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS260088-96StripWells 96-Strip-Wells
EUR 450

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS212234-02mg 0.2mg
EUR 500

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS212234-5x02mg 5x0.2mg
EUR 2070

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS215105-0025mg 0.025mg
EUR 210

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS215105-5x0025mg 5x0.025mg
EUR 765

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS213386-01mg 0.1mg
EUR 920

MOUSE ANTI HUMAN INTEGRIN ALPHA 9 BETA 1

MBS213386-5x01mg 5x0.1mg
EUR 3965

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-48StripWells 48-Strip-Wells
EUR 550

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363745-96StripWells 96-Strip-Wells
EUR 765

Donkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9343685-INQUIRE INQUIRE Ask for price

Pigeon Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349426-INQUIRE INQUIRE Ask for price

Rabbit Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9349793-INQUIRE INQUIRE Ask for price

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-48StripWells 48-Strip-Wells
EUR 550

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9355041-96StripWells 96-Strip-Wells
EUR 765

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-48StripWells 48-Strip-Wells
EUR 550

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9344945-96StripWells 96-Strip-Wells
EUR 765

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-10x96StripWells 10x96-Strip-Wells
EUR 3545

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-48StripWells 48-Strip-Wells
EUR 310

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-5x96StripWells 5x96-Strip-Wells
EUR 1940

Rabbit Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS2600049-96StripWells 96-Strip-Wells
EUR 475

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-10x96StripWells 10x96-Strip-Wells
EUR 3955

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-48StripWells 48-Strip-Wells
EUR 305

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-5x96StripWells 5x96-Strip-Wells
EUR 2005

Rat Integrin Alpha 5 Beta 3 ELISA Kit

MBS1603472-96StripWells 96-Strip-Wells
EUR 475

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-48StripWells 48-Strip-Wells
EUR 550

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9362218-96StripWells 96-Strip-Wells
EUR 765

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-48StripWells 48-Strip-Wells
EUR 550

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9363195-96StripWells 96-Strip-Wells
EUR 765

Chicken Integrin Alpha V Beta 3 (ITGAVB3) ELISA Kit

MBS9353364-INQUIRE INQUIRE Ask for price

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-10x96StripWells 10x96-Strip-Wells
EUR 3545

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-48StripWells 48-Strip-Wells
EUR 310

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-5x96StripWells 5x96-Strip-Wells
EUR 1940

Porcine Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS269083-96StripWells 96-Strip-Wells
EUR 475

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-10x96StripWells 10x96-Strip-Wells
EUR 3545

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-48StripWells 48-Strip-Wells
EUR 310

Chicken Integrin alpha V beta3 (ITG alpha V beta3) ELISA Kit

MBS266731-5x96StripWells 5x96-Strip-Wells
EUR 1940

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